Applied Chemistryhttps://dyuthi.cusat.ac.in:443/xmlui/handle/purl/4142024-02-07T16:33:29Z2024-02-07T16:33:29ZElectrochemical studies of tamsulosin hydrochloride using multiwalled carbon nanotube-modified glassy carbon sensorGirish Kumar,KThomas, DJoseph, RIssac, SLonappan, Lhttps://dyuthi.cusat.ac.in:443/xmlui/handle/purl/47082014-09-20T20:30:29Z2011-10-10T00:00:00ZElectrochemical studies of tamsulosin hydrochloride using multiwalled carbon nanotube-modified glassy carbon sensor
Girish Kumar,K; Thomas, D; Joseph, R; Issac, S; Lonappan, L
A differential pulse voltammetric sensor for the determination of tamsulosin hydrochloride (TAM) using multiwalled carbon nanotubes
(MWNTs)–Nafion-modified glassy carbon electrode (GCE) has been developed. MWNTs were dispersed in water with the help of Nafion
and were used to modify the surface of GCE via solvent evaporation. At MWNT-modified electrode, TAM gave a well-defined oxidation
peak at a potential of 1084 mV in 0.1 M acetate buffer solution of pH 5. Compared to the bare electrode, the peak current of TAM
showed a marked increase and the peak potential showed a negative deviation. The determination conditions, such as the amount of
MWNT–Nafion suspension, pH of the supporting electrolyte and scan rate, were optimised. Under optimum conditions, the oxidation
peak current was proportional to the concentration of TAM in the range 1 × 1023 M–3 × 1027 M with a detection limit of
9.8 × 1028 M. The developed sensor showed good stability, selectivity and was successfully used for the determination of TAM in pharmaceutical
formulations and urine samples
Micro & Nano Letters, 2011, Vol. 6, Iss. 10, pp. 867–870
2011-10-10T00:00:00ZSyntheses, EPR spectral studies and crystal structures of manganese(II) complexes of neutral N,N donor bidentate Schiff bases and azide/thiocyanate as coligandPrathapachandra Kurup, M RSreesha, SasiSithambaresan, MFun, H Khttps://dyuthi.cusat.ac.in:443/xmlui/handle/purl/47072014-09-20T20:30:27Z2010-01-01T00:00:00ZSyntheses, EPR spectral studies and crystal structures of manganese(II) complexes of neutral N,N donor bidentate Schiff bases and azide/thiocyanate as coligand
Prathapachandra Kurup, M R; Sreesha, Sasi; Sithambaresan, M; Fun, H K
Four manganese(II) complexes Mn2(paa)2(N3)4 (1), [Mn(paa)2(NCS)2] 3/2H2O (2), Mn(papea)2(NCS)2 (3),
[Mn(dpka)2(NCS)2] 1/2H2O(4) of three neutral N,N donor bidentate Schiff bases were synthesized and physico-
chemically characterized by means of partial elemental analyses, electronic, infrared and EPR spectral
studies. Compounds 3 and 4 were obtained as single crystals suitable for X-ray diffraction. Compound 4
recrystallized as Mn(dpka)2(NCS)2. Both the compounds crystallized in the monoclinic space groups P21
for 3 and C2/c for 4. Manganese(II) is found to be in a distorted octahedral geometry in both the monomeric
complexes with thiocyanate anion as a terminal ligand coordinating through the nitrogen atom. EPR spectra
in DMF solutions at 77 K show hyperfine sextets with low intensity forbidden lines lying between each
of the two main hyperfine lines and the zero field splitting parameters (D and E) were calculated.
Polyhedron 29 (2010) 2643–2650
2010-01-01T00:00:00ZMn(II) complexes of some acylhydrazones with NNO donor sites: Syntheses, a spectroscopic view on their coordination possibilities and crystal structuresPrathapachandra Kurup, M RSheeja, S RNeema, Ani Mangalamhttps://dyuthi.cusat.ac.in:443/xmlui/handle/purl/47062014-09-20T20:30:31Z2010-01-01T00:00:00ZMn(II) complexes of some acylhydrazones with NNO donor sites: Syntheses, a spectroscopic view on their coordination possibilities and crystal structures
Prathapachandra Kurup, M R; Sheeja, S R; Neema, Ani Mangalam
Mn(II) complexes derived from a set of acylhydrazones were synthesised and characterized by elemental
analyzes, IR, UV–vis and X-band EPR spectral studies as well as conductivity and magnetic susceptibility
measurements. In the reported complexes, the hydrazones exist either in the keto or enolate form, as evidenced
by IR spectral data. Crystal structures of two complexes are well established using single crystal
X-ray diffraction studies. In both of these complexes two equivalent monoanionic ligands are coordinated
in a meridional fashion using cis pyridyl, trans azomethine nitrogen and cis enolate oxygen atoms positioned
very nearly perpendicular to each other. EPR spectra in DMF solutions at 77 K show hyperfine sextets
and in some of the complexes the low intensity forbidden lines lying between each of the two
hyperfine lines are also observed
Polyhedron 29 (2010) 3318–3323
2010-01-01T00:00:00ZSynthesis, spectral characterization and crystal structure of copper(II) complexes of 2-benzoylpyridine-N(4)-phenylsemicarbazonePrathapachandra Kurup, M RBinu, VargheseSithambaresan, MSuja, KrishnanSheeja, S REringathodi, Sureshhttps://dyuthi.cusat.ac.in:443/xmlui/handle/purl/47052014-09-20T20:30:31Z2011-01-01T00:00:00ZSynthesis, spectral characterization and crystal structure of copper(II) complexes of 2-benzoylpyridine-N(4)-phenylsemicarbazone
Prathapachandra Kurup, M R; Binu, Varghese; Sithambaresan, M; Suja, Krishnan; Sheeja, S R; Eringathodi, Suresh
An interesting series of nine new copper(II) complexes [Cu2L2(OAc)2] H2O (1), [CuLNCS] ½H2O (2), [CuLNO3]
½H2O (3), [Cu(HL)Cl2] H2O (4), [Cu2(HL)2(SO4)2] 4H2O (5), [CuLClO4] ½H2O (6), [CuLBr] 2H2O (7),
[CuL2] H2O (8) and [CuLN3] CH3OH (9) of 2-benzoylpyridine-N(4)-phenyl semicarbazone (HL) have been
synthesized and physico-chemically characterized. The tridentate character of the semicarbazone is
inferred from IR spectra. Based on the EPR studies, spin Hamiltonian and bonding parameters have been
calculated. The g values, calculated for all the complexes in frozen DMF, indicate the presence of the
unpaired electron in the dx2 y2 orbital. The structure of the compound, [Cu2L2(OAc)2] (1a) has been
resolved using single crystal X-ray diffraction studies. The crystal structure revealed monoclinic space
group P21/n. The coordination geometry about the copper(II) in 1a is distorted square pyramidal with
one pyridine nitrogen atom, the imino nitrogen, enolate oxygen and acetate oxygen in the basal plane,
an acetate oxygen form adjacent moiety occupies the apical position, serving as a bridge to form a centrosymmetric
dimeric structure
Polyhedron 30 (2011) 70–78
2011-01-01T00:00:00Z