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Abstract:
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A series of nonelectrolytic lanthanide(III) complexes,
[
ML
2
Cl
3
]
·
2
H
2
O, where M is lanthanum(III),
praseodymium(III), neodymium(III), samarium(III), gadolinium(III), terbium(III), dysprosium(III), and
yttrium(III), containing sulfamethoxazole ligand (L) are prepared. The structure and bonding of the ligand are
studied by elemental analysis, magnetic susceptibility measurements, IR,
1
H NMR,
TG
/
DTA
, X-ray diffraction
studies, and electronic spectra of the complexes. The stereochemistry around the metal ions is a monocapped
trigonal prism in which four of the coordination sites are occupied by two each from two chelating ligands, sulfonyl
oxygen, and nitrogen of the amide group and the remaining three positions are occupied by three chlorines.
The ligand and the new complexes were tested in
vitro to evaluate their activity against the bacteria
Escherichia
coli
and
Staphylococcus
aureus. |